I have a ProLite Plus. I don't think I could do a NeoAir. All that work just to save 10 ounces.
I love my NeoAir. It is one of my favorite pieces of gear. It packs to the size of a waterbottle, weighs 10 ounces less than the Prolite Plus, and is much more comfortable.
I really don't get the fuss over inflating it and have a hard time thinking of 15 breaths as "All that work". It takes all of 30 seconds to inflate.
So far my only complaint is that it was expensive, but It is so much nicer than my regular Thermarest that I think it was well worth it. That says a lot because I am a bit of a cheapskate and usually lean toward fairly inexpensive gear.