I agree it's critical to start early to avoid the heat and gusty winds. I started WE/Nevada each day before 5am which got me halfway to my day's destination before things warmed up each day. The Nevada portion of WE is mostly on very quiet roads with little to no traffic to worry about when riding in early morning darkness. I recall leaving Austin, NV and riding for 2 hours before the first car drove past me.
Also important to factor the elevation. This is High Desert country and you will spend your days between 4000' and 7000' with about 3 mountain passes to deal with each day in Nevada. Not steep climbs, quite mellow actually, but something to consider during your planning.