I'm not familiar with the Woods Line state trail so I can't comment on it. I'm familiar with the 395 from Reno to Southern California. When I drive up to Tahoe I like to take the 395.
Between Reno and Carson City you may want to check out the following website to see where bicycles are prohibited http://www.bicyclenevada.com/restrict.html
. South of Carson the road is pretty good and it generally (but not always) has a wide shoulder (although the state has installed rumble strips). There are several campgrounds along the way and in other areas you could probrobly camp out of site of the road and no one will bother you. The scenery is pretty good until you get close to Ridgecrest when it really becomes what is called high desert. You will also find at least 2 good sized climbs.
There is one 30 mile stretch I don't recommend because of high traffic and no shoulder. That is between Kramer Junction (Hwy 58) and Victorville.