I agree with what has been posted.
To add: I rode the WE route solo from Sacramento to Baker, NV a couple of months ago...then went on to SLC. Most of the traffic gives ample room as they pass...and most of them wave to you. You might get tired of waving back...I did. The good news is you can see them and sometimes hear them coming for miles. The only problem I encountered was when 2 opposite direction trucks or RVs ( the worst) happened to meet at the same spot I was. In this case they stay in their lane and leave little room for you. Cars are OK but trucks and RVs generate a substantial wake and the blast of wind, particularly when there is a crosswind blowing from your left, is mighty. This is where a mirror is very helpful to anticipate the "perfect storm" scenario and pull off the road to let the trucks pass. Happened to me several times on the way to Salt Lake City and once I figured this out I learned to relax a lot more.
As others have said the shoulder on US 50 is for the most part good. The comment about Carson City to Sand Mountain is accurate. The shoulder and rumble strip configuration changes from county to county. Some better than others.
Biggest surprise? The "Loneliest Road" really isn't very lonely any more. I began riding each day at sunrise and had the road to myself for the first couple of hours but once the day got cranked up had a car/truck/RV go by me about every 5 or 10 minutes.
My favorite bit? Between Austin, NV and Middlegate is route 722...the old highway. Spent 5 hours on this road and counted 3 cars. A beautiful ride.
Caution: no bike shops along US 50 in NV until you hit Carson City.
I believe there was a 3 day stretch between about Fallon and Ely without cell phone service.
If you haven't already try searching this forum for other WE discussions. I found a lot of good stuff here before my ride specific to this route.
An excellent ride and great adventure. You will enjoy. If you would like to see the daily blog I wrote during this ride contact me at email@example.com
and I will forward the link to you.