The nose-less saddles do work, but you may lose some control over the bike. You may not realize it, but the primary use of the saddle nose to help push the bike over or keep it upright while turning. Since most loaded touring bikes aren't attempting the type of maneuvers that require large amounts of "saddle steering", it probably won't make much of a difference. You can also accomplish the same thing by pushing against the top tube with your knee.
If you plan on spending many miles on one of those saddles, be wary of ones that are very soft. Yo will sink right through them and that soft padding will migrate to other areas were you don't want it. Some triathelets are now using a similar saddle calle dthe Adamo. I don't know what saddles you've tried, but maybe a firmer, wider saddle would also work.