If you are gping to Maine you will have to consider that, if you were to do the TransAm, you would then have to head north through some heavily populated areas. I did the entire NT in '99 and it was terrific. I then took the Atlantic Coast Route home to Philadelphia. I have also done the TA from Missoula to Fairplay, CO. As one poster noted, every route will have its good points and bad points. While the TA will give you more majestic mountain scenery out west, you won't get to do the North Cascades Highway or Going to the Sun Road (my personal favorite) and Chief Mountain Road. And for quiet roads, not much beats the rolling hills of North Dakota, which has a population of less than 650,000 people.