You can cycle south on one coast and north on the other coast. Cross the Everglades and look out for alligtaors, pythons, snakes, and yes, the panther population is beginning to rebound, they say. Orlando is mad with traffic. I would avoid Hwy. 27. It is a curse in some stretches. The Keys are really nice for cycling. I would use Card Sound Road for getting to them, not US1. Use 1 to past the Last Chance Saloon, if that is what they are still calling it, and then Card Sound Road. Hwy. 1 might have been widened since last I cycled that way. It was hell. Sure it had a shoulder, but lines of cat-eye reflectors made it a pain to cycle. There is a Withlacoochee bike trail near the west coast.