If there is more than one person to share the driving and cost, a car becomes a pretty reasonable option. It is less so for one person, especially given the long drive. It has worked well for me when traveling with two companions.
Taking a train might also be an option. Amtrak worked out very well for a leg of my spring tour. Be careful to verify that they will load and unload baggage at both ends or each leg done by rail. I liked that they were willing to switch the dates of my ticket with no fuss or fees, even at very short notice. They supplied a huge box for a small fee. It was so big that I only had to take off the pedals and turn the handlebar. I didn't even need to remove racks or lower the seat. It was all really convenient and I had no complaints at all. That said I have only done it once.